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Research investigations have demonstrated that a range of nutraceutical and botanical therapeutic agents exhibit anti-viral activity and immune support.1-3 In addition, ongoing studies of specific pharmaceutical drug treatments have highlighted potential viral defense and immunomodulatory impacts.4,5 IFM’s new online, on-demand course, Resistance, Resilience, and Recovery: Patient Care in a Pandemic, highlights these therapeutic agents and their mechanisms of action as they relate to viral activity.
Interrupting Viral Mechanisms
As part of this new course, a team of experienced educators share the latest research on specific therapeutic agents that target various viral mechanisms. These experts not only explore functional medicine interventions that augment conventional approaches, but also lead deep dive discussions into topics such as ACE-2 docking, furin cleavage inhibition, the viral replication cycle and its interruption, and potential clinical applications to support improved patient outcomes. Educators and topics include:
- Robert Luby, MD, IFMCP – Functional Medicine Interventional Mechanisms of Action
- Gary Goldman, MD, FACOG, IFMCP – Pharmaceutical Mechanisms of Action
- Joel Evans, MD, IFMCP – Botanical and Nutraceutical Mechanisms of Action
Understanding how specific pharmaceuticals, botanicals, and nutraceuticals work to support a patient’s immune response, fight viral infection, and potentially improve resiliency helps to inform and enhance the clinical guidance and recommendations provided as personalized treatment strategies during this pandemic. Explore the latest investigations and stay informed of emerging research on COVID-19 by signing up for IFM’s course, Resistance, Resilience, and Recovery: Patient Care in a Pandemic.
- Lin CJ, Lin HJ, Chen TH, et al. Polygonum cuspidatum and its active components inhibit replication of the influenza virus through toll-like receptor 9-induced interferon beta expression. PLoS One. 2015;10(2):e0117602. doi:10.1371/journal.pone.0117602 [published correction appears in PLoS One. 2015;10(4):e0125288. doi:10.1371/journal.pone.0125288].
- Somerville VS, Braakhuis AJ, Hopkins WG. Effect of flavonoids on upper respiratory tract infections and immune function: a systematic review and meta-analysis. Adv Nutr. 2016;7(3):488-497. doi:10.3945/an.115.010538
- Kunnumakkara AB, Bordoloi D, Padmavathi G, et al. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol. 2017;174(11):1325-1348. doi:10.1111/bph.13621
- Coughlin MM, Prabhakar BS. Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential. Rev Med Virol. 2012;22(1):2-17. doi:10.1002/rmv.706
- Al-Bari MAA. Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases. Pharmacol Res Perspect. 2017;5(1):e00293. doi:10.1002/prp2.293