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Potential Micronutrient Deficiencies Associated With PPI Use

Online Course

Proton pump inhibitors (PPIs) are commonly prescribed as part of the treatment plan for conditions like GERD and H. pylori infection where acid suppression is necessary. As they reduce the secretion of acid in the stomach, PPIs may increase the risk for hypochlorhydria (suboptimal stomach acid levels). Low levels of stomach acid may begin to impair the body’s ability to digest food properly and absorb nutrients.

Potential Micronutrient Deficiencies Associated With PPI Use explores the potential micronutrient deficiencies that occur in long-term and acute use of PPIs. Clinicians will learn to identify clinical indicators of nutrient deficiency and work through the next steps for addressing it.

Consider this: Eleanor is a 71-year-old patient who has been taking a PPI to help manage her heartburn. She presents with tingling in her fingers and says she has been feeling weak and forgetful lately. You notice the palms of her hands are paler than usual. Eleanor’s magnesium and iron levels came back normal, but could she be deficient in another key micronutrient? Several case vignettes like this will guide clinicians through initiating a nutrition intervention, lifestyle changes, or further testing.

This free online learning module offers:

  • Clinical awareness of potential nutrient depletion associated with PPI usage.
  • A focus on matching signs and symptoms to potential nutrient deficiencies.
  • Additional functional medicine resources, including patient and clinician-facing resources for initiating nutrition and lifestyle change.


Read more about the functional medicine approach to PPIs and how to safely deprescribe patients when clinically indicated.

GERD: Weighing Benefits and Risks of Treatment Options

The Importance of Digestion & Nutrition in Chronic Disease



Additional Information

What Clinicians Will Learn

By the end of this brief course, clinicians will be able to:

  • Identify signs and symptoms of micronutrient deficiencies that may be associated with PPI use.
  • Identify useful lab analytes that may indicate common micronutrient deficiencies.
  • Create treatment plans to replete selected micronutrients using food sources.

Who Should Take This Course?

A multimodal approach to assessing physiological dysfunction is a critical first step in addressing the root causes of disease. This course is intended for licensed healthcare practitioners who order and interpret labs, and counsel patients on nutrition within the scope of their practice. Assessing the nutrient status of patients is an important skill for many care providers, even those who may not order labs. All care team members can benefit from learnings in this course such as:

  • Nurse practitioners
  • Nutrition professionals (RD, CNS, CN, and others with advanced degrees from accredited universities)
  • Pharmacists
  • Physician assistants
  • Physicians (MDs, NDs, DOs, DCs)
  • Registered nurses

Course Policy

  • Your course will be delivered electronically to your online account directly upon purchase.
  • You will have access to the course for 60 days from the date of purchase.
Return Policy
Cancellation Request Received Eligible Refund
*After purchase No Refund
*Given the nature of digital items, refunds or credits on this purchase are not permitted.