News & Insights

Functional Medicine News & Emerging Research

Insights
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Understanding the Mind-Body Connection Can Help GI Patients

Given the strong mind-body/brain-gut connection, it is clear that when the normal integrity of the GI tract is compromised, distant systemic complaints can result, even in the absence of overt GI symptoms. Integrative approaches may be helpful for reducing symptoms and reestablishing a healthy gut and a healthy mind.

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The Gut-Brain Axis & Systems Biology

The gut-brain axis is the bidirectional communication between the gut and the brain, which occurs through multiple pathways that include hormonal, neural, and immune mediators. Interestingly, the signals along this axis can originate in the gut, the brain, or both, with the objective of maintaining normal gut function and appropriate behavior. 

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The 5R Framework for Gut Health

This video introduction to the 5R framework for treating digestive disorders is presented by Vincent Pedre, MD.

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Histamine-Related Reactions

Histamine reactions can manifest as many different symptoms. Dr. Board describes her experience treating patients with histamine reactions.
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An Ulcerative Colitis Case

After suffering from ulcerative colitis for several years, a patient arrived at the clinic of Robert Rountree, MD. Dr. Rountree practices Functional Medicine, and his approach yielded good results with this patient – watch the video to learn more.

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Framework for Treating GI Issues

As an educator at IFM’s GI Advanced Practice Module (APM), Tom Sult, MD, is an expert in treating simple and complex gastrointestinal problems. In this video, he explains the DIGIN framework, a cornerstone of GI treatment.

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The Role of the Microbiome in Immune-Related Diseases

How does the microbiome interact with the immune system, and how do these interactions help determine a state of health or disease in the body? In this article, Kara Fitzgerald, ND, and Romilly Hodges, CNS, discuss how cross-talk between the microbiome and cells in the intestinal mucosal immune system is important for immune system maturation and modulation across all developmental stages.

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Rates of Celiac Disease Continue to Rise Worldwide

How Celiac Research Changed Estimated Prevalence Rates with Alessio Fasano, MDOver the last few decades, rates of celiac disease have grown where it is now considered a major public health problem worldwide. What are the autoimmune triggers and how can Functional Medicine affect epidemic? READ MORE
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Understanding & Diagnosing Functional Dyspepsia

Understanding and Diagnosing Functional DyspepsiaBecause dyspepsia can manifest in a multitude of symptoms, clinicians are encouraged to look for red flags that are clinical indicators of a possible serious underlying condition. Yet on diagnostic work-up, only 20 to 30% of patients with dyspepsia are found to have frank diseases that account for their symptoms. READ MORE
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Intestinal Permeability & Associated Diseases

Crohn’s disease and ulcerative colitis, collectively called inflammatory bowel disease (IBD), are immune-mediated conditions characterized by a chronic inflammation of the gut. Increased intestinal permeability has been shown to play a central role in the pathogenesis of IBD. What are the mechanisms by which intestinal permeability contributes to the pathophysiology of disease, and what can clinicians do about it?

Dietary changes, chronic alcohol consumption, stress, the use of antibiotics, and other environmental factors, as well as genetic factors, can lead to alterations in the gut microbiota, which in turn may induce intestinal inflammation and increase intestinal permeability. As clinicians, how can we help patients with dysbiotic microbiota?

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The Microbiome, Stress Hormones, & Gut Function

Stress affects gastrointestinal function in both healthy adults and in patients with GI conditions. Lifestyle interventions may help.

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Stress, Bile Acids, and IBS Symptoms

Bile acids (BA) have a significant effect on gut motility, sensory, and secretory functions, intestinal permeability, and inflammatory response regulation. For patients with IBS, understanding the role of bile acids can inform treatment.

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