News & Insights

Functional Medicine News & Emerging Research

Insights
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The Role of the Microbiome in Immune-Related Diseases

How does the microbiome interact with the immune system, and how do these interactions help determine a state of health or disease in the body? In this article, Kara Fitzgerald, ND, and Romilly Hodges, CNS, discuss how cross-talk between the microbiome and cells in the intestinal mucosal immune system is important for immune system maturation and modulation across all developmental stages.

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Rates of Celiac Disease Continue to Rise Worldwide

How Celiac Research Changed Estimated Prevalence Rates with Alessio Fasano, MDOver the last few decades, rates of celiac disease have grown where it is now considered a major public health problem worldwide. What are the autoimmune triggers and how can Functional Medicine affect epidemic? READ MORE
News

Applying Functional Medicine in Clinical Practice (AFMCP)

New Online Dates Announced!

The premier course in Functional Medicine, Applying Functional Medicine in Clinical Practice (AFMCP), provides practitioners with Functional Medicine training—and IFM has now made it available both in-person and online.

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Understanding & Diagnosing Functional Dyspepsia

Understanding and Diagnosing Functional DyspepsiaBecause dyspepsia can manifest in a multitude of symptoms, clinicians are encouraged to look for red flags that are clinical indicators of a possible serious underlying condition. Yet on diagnostic work-up, only 20 to 30% of patients with dyspepsia are found to have frank diseases that account for their symptoms. READ MORE
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Intestinal Permeability & Associated Diseases

Red Flags Intestinal Permeability Robert Sheeler MDDietary changes, chronic alcohol consumption, stress, the use of antibiotics, and other environmental factors, as well as genetic factors, can lead to alterations in the gut microbiota, which in turn may induce intestinal inflammation and increase intestinal permeability. As clinicians, how can we help patients with dysbiotic microbiota? READ MORE
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How Stress Changes Gut Function

What dietary and lifestyle interventions can help to diminish the effects of stress within the body and affect gastrointestinal function? New evidence suggests that both prebiotic diets and exercise interventions are most effective if given early in life when the gut and brain are more plastic. READ MORE
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Stress, Bile Acids, and IBS Symptoms

Bile absorption difficulties are common in patients with irritable bowel syndrome, as are anxiety and depression. When and how should treatment address these concerns? READ MORE
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Gut Dysbiosis and Stress

Once thought to be extraneous to the body, stress is now seen as another symptom of dysbiosis. Learn cost-effective strategies for resolving stress and gut-based diseases. READ MORE

How Cholera Research Uncovered Zonulin

The Discovery of Zonulin a Mediator of Intestinal Permeability and Chronic Inflammatory Diseases with Alessio Fasano, MDAlessio Fasano, MD, was researching cholera when the research in his lab revealed a new factor contributing to intestinal permeability: zonulin. In this interview with Patrick Hanaway, MD, Dr. Fasano describes how the path to uncovering zonulin was one of serendipity and open-mindedness. Read More
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The Importance of Digestion in Chronic Disease

Physiology of Digestion Kara Parker MDClose to 100 million Americans suffer from some form of digestive problem. How can practitioners incorporate new research on barrier integrity, digestion, absorption, gut flora, and nutritional insufficiencies in the diagnosis and management of patients with digestive dysfunction and chronic diseases? Read More
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New Research in the Field of Neurogastroenterology

In 2017, for the first time in humans, UCLA researchers established an association between gut microbiota and brain regions involved in processing sensory information. The study showed that differences in gut microbial composition correlate with regional brain volumes in patients with irritable bowel syndrome and shed light on the connections between childhood trauma, brain development, and gut microbiome composition. Read More
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Alternatives to PPIs and H2 Blockers

Taking an over-the-counter acid blocker for occasional heartburn symptoms may not be a big issue, but in practice, many patients with chronic reflux are prescribed acid blockers indefinitely. Research suggests that this long-term approach may have significant drawbacks. Read More